How Much do DNA Segments Differ Between 23andMe and MyHeritage?


Three chromosome segments with overlay chromosome start and end points

When reviewing your DNA match results, have you ever wondered where exactly a DNA segment starts and ends? Have you also wondered whether or not that's important?


Genetic Genealogists Use DNA Segments to Triangulate Matches


Many genetic genealogists use DNA matching segments to determine if individuals share a common ancestor.


For example, Devon and her 2nd Cousin, David, share the same start point and endpoint on Chromosome 12. She can then use that segment to see what other DNA cousins have the same or an overlapping DNA segment in the same location. Then genetic triangulation occurs, and these DNA matches share a common ancestor. The only question is who.


What Happens When DNA Segment End Points Differ Between Companies


However, what happens when 23andMe and MyHeritage don't report the same start and end point?


What happens if you import your data from Ancestry, 23andMe, MyHeritage, or other tests into GEDmatch, and your start and end points vary? Can you be confident in your triangulation efforts and relationship conclusions?



Video Thumbnail for: Do Chromosome Segment End Points Matter in Genetic Genealogy?

In this video, Andy uses his and his brother's data to compare 23andMe, MyHeritage, and GEDmatch, focusing primarily on one chromosome and the start and endpoints each company reports.


As you watch this video, you'll see the following chart.

DNA Start and Endpoint Comparison Table with data from 23andMe MyHeritage Gedmatch

Click on the image above to expand it to see a clear view of the table Andy discusses.


In this video, Andy will review the:

  • inconsistencies between each company

  • possible reasons for the inconsistencies

  • why the inconsistences don't necessarily matter

  • whether start and endpoint comparisons are useful.


↪️ Confused about DNA and genealogy?

Grab your copy of this FREE DNA guide:

DNA strand with the title Free Guide Answers to the Most Common DNA Questions asked by new genealogists

For more genetic genealogy training, check out the following.



Note: To leave a comment, you will be asked to sign in with your Facebook or Google Account. This action will help reduce spam comments on our site. I hope you'll understand.